AhR-ZPROSTŘEDKOVANÁ AKTIVITA HUMINOVÝCH LÁTEK A JEJICH FOTODEGRADAČNÍCH PRODUKTŮ

• Title in English: AhR-MEDIATED ACTIVITY OF HUMIC SUBSTANCES AND THEIR PHOTO-DEGRADATION PRODUCTS
• Authors: BITTNER Michal; HILSCHEROVÁ Klára; GIESY John, P.
• Year of publication: 2007
• Type: Article in Proceedings
• Conference: Bulletin VÚRH Vodňany
• MU Faculty or unit: Faculty of Science
• Field: Water pollution and control
• Keywords: Humic Substances; Irradiation; AhR-mediated activity
• Description: Humic substances (HS) are ubiquitous in the environment - they constitute the major components of dissolved organic matter in waters and the major part of materials that comprise soil organic matter. However, some studies indicate that HS can induce a direct adverse effect on human health and hormone-like effects on fish, amphibians and invertebrates. HS molecules contain number of aromatic rings and conjugated double bonds - the so called chromophores. That implies irradiation of dissolved HS can lead to a series of photochemical reactions which can act on the HS itself, or on other substances present in aquatic environment along with HS such as e.g. xenobiotics. In this contribution, we summarize our new findings on alteration of AhR-mediated activity of irradiated HS under the lab conditions. Additionally, supposed mechanisms of observed irradiation-induced decrease in AhR-mediated activity of dissolved HS are discussed.

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