Publication details
Kognitivní funkce u pacientů s unipolární depresivní poruchou v remisi
| Title in English | Cognitive functions in patients with unipolar depression in remission |
|---|---|
| Authors | |
| Year of publication | 2008 |
| Type | Article in Periodical |
| Magazine / Source | Psychiatrie |
| MU Faculty or unit | |
| Citation | |
| Field | Psychiatry, sexuology |
| Keywords | major depressive episode;remission;cognitive function; course of illness;outcome |
| Description | The present study investigates performance of verbal memory, attention and executive functions during remission from unipolar major depressive episodes (MDD). We tested a hypothesis that outpatients do not differ in cognitive variables from matched controls, in a well defined outpatient sample, consisting of medicated and unmedicated patients with a history of MDD living in their natural environments. 97 fully remitted patients with MDD were compared to 97 healthy control subjects matched for education, age and gender on the Auditory Verbal Learning Test (AVLT) and the Trail Making Test (TMT). 1/3 of the patients scored as cognitively impaired; however one out of every six to nine patients received results above 1 SD of controls sample. In stating deficits the performance of patients did not differ much when compaired to controls and official norms except in short-term memory, where we found fewer deficits than in controls, according to official norms. Our findings indicate that we may trust more in the patients self-analysis of his/her decreased cognitive performance. |