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Publication details
Proteomická analýza a její využití ve výzkumu mnohočetného myelomu
Title in English | Proteomics and its application in multiple myeloma research |
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Authors | |
Year of publication | 2008 |
Type | Article in Periodical |
Magazine / Source | Klinická onkologie Supplement 2008 |
MU Faculty or unit | |
Citation | |
Field | Oncology and hematology |
Keywords | proteomics; two-dimensional gel electrophoresis; protein identification; multiple myeloma; plasma |
Description | Two-dimensional gel electrophoresis combined with mass spectrometry has become a fundamental technique for the study of protein expression. Proteomic analysis of plasma cells or plasmatic proteins can be done before and after treatment. Proteomics offers the possibility of identification of disease-associated protein markers for prognostic evaluation and for the selection of targets for specific drug therapy. |
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