A putative DRD3 schizophrenia risk haplotype deconstructed

• Authors: SAND Phillip; LANGGUTH Berthold; PŘIKRYL Radovan; KUČEROVÁ Hana; ČEŠKOVÁ Eva
• Year of publication: 2008
• Type: Article in Periodical
• Magazine / Source: Biological Psychiatry
• MU Faculty or unit: Faculty of Medicine
• Field: Psychiatry, sexuology
• Keywords: DRD3; haplotype; schizophrenia
• Description: Meta-analyses have suggested an association between schizophrenia (SZ) and a coding polymorphism (rs6280/Ser9Gly) at the dopamine D3 receptor gene (DRD3), but results have been inconsistent. Because most studies have evaluated only rs6280, the inconsistencies might reflect associations with other variants.

Related projects

• The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.