Characterization of a GM7 glioblastoma cell line showing CD133 positivity and both cytoplasmic and nuclear location of nestin

• Authors: LOJA Tomáš; CHLAPEK Petr; KUGLÍK Petr; PEŠÁKOVÁ Martina; OLTOVÁ Alexandra; CEJPEK Pavel; VESELSKÁ Renata
• Year of publication: 2009
• Type: Article in Periodical
• Magazine / Source: Oncology Reports
• MU Faculty or unit: Faculty of Science
• Field: Oncology and hematology
• Keywords: nestin; CD133; intermediate filaments; glioblastoma multiforme; cancer stem cells; immunocytochemistry; transmission electron microscopy
• Description: A detailed characterization of the established GM7 glioblastoma cell line is given in this paper. This cell line was identified as near-triploid and is characterized by nestin+/CD133+ phenotype with unusual localization of nestin both in cytoplasm and cell nucleus.

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