Publication details

Telomerase Activity in Head and Neck Cancer

Authors

KUNICKÁ Zuzana MUCHA Igor FAJKUS Jiří

Year of publication 2008
Type Article in Periodical
Magazine / Source Anticancer Research
MU Faculty or unit

Faculty of Science

Citation
Field Genetics and molecular biology
Keywords Telomerase activity; head and neck cancer; real-time TRAP; prognosis; marker
Description Telomerase activity was determined using quantitative TRAP method in 58 patients with head and neck cancer. Tumours were positive in 88%. Value of telomerase activity was compared with standard histopatological parametres (T stage, N stage, grade). Measurement ot telomerase activity in tumours and tumour adjacent tissues may be better parameter of tumour agresivity than standard grading.

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