Publication details

NR1 podjednotka NMDA receptoru v hipokampech osob trpících schizofrenií. Faktor věku, pohlaví a medikace

Title in English NR1 subunit of NMDA receptor in hippocampus of schizophrenics. Age, sex and medication factors
Authors

VRAJOVÁ Monika LOCHMAN Jan ŠERÝ Omar MAJER Emil PEKOVÁ Šoňa ŠŤASTNÝ František

Year of publication 2009
Type Article in Proceedings
Conference Psychiatrie
MU Faculty or unit

Faculty of Science

Citation
Field Neurology, neurosurgery, neurosciences
Keywords NR1 schizophrenia subunit receptor NMDA
Description This article is focused on results of our schizophrenia research on brains of schizophrenics. Protein expression of GluN1C2 isoform showed similarly significant interaction of laterality and gender as panGluN1 (F[1,25] = 9.32, P = 0.0053) (control vs. med-schizophrenia vs. non-med-schizophrenia). In group of man was also significant difference in laterality (F [1, 14] = 5.47, P = 0.0346) (control vs. schizophrenics) while in the woman group the laterality was not significant.

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