Nestin expression in osteosarcomas and derivation of nestin/CD133 positive osteosarcoma cell lines.

• Authors: VESELSKÁ Renata; HERMANOVÁ Markéta; LOJA Tomáš; CHLAPEK Petr; ZAMBO Iva; VESELÝ Karel; ZITTERBART Karel; ŠTĚRBA Jaroslav
• Year of publication: 2008
• Type: Article in Periodical
• Magazine / Source: BMC Cancer
• MU Faculty or unit: Faculty of Science
• Citation: VESELSKÁ, Renata, Markéta HERMANOVÁ, Tomáš LOJA, Petr CHLAPEK, Iva ZAMBO, Karel VESELÝ, Karel ZITTERBART and Jaroslav ŠTĚRBA. Nestin expression in osteosarcomas and derivation of nestin/CD133 positive osteosarcoma cell lines. BMC Cancer. 2008, vol. 8, No 300, 8 pp. ISSN 1471-2407.
• web: http://www.biomedcentral.com/1471-2407/8/300
• Field: Oncology and hematology
• Keywords: nestin; CD133; intermediate filaments; osteosarcoma; immunocytochemistry; immunohistochemistry; cancer stem cells
• Description: Immunohistochemical and immunocytochemical methods demonstrate the expression of nestin, the intermediate filament protein class VI, in osteosarcomas. Osteosarcoma cell lines showing nestin+/CD133+ phenotype were successfully derived from these tumors.

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