Postavení milnacipranu v klinické praxi

• Title in English: The Position of Milnacipran in Clinical Practice
• Authors: ČEŠKOVÁ Eva
• Year of publication: 2008
• Type: Article in Periodical
• Magazine / Source: Česká a slovenská psychiatrie
• MU Faculty or unit: Faculty of Medicine
• Field: Psychiatry, sexuology
• Keywords: ilnacipran; antidepressants; fibromyalgia; pharmacokinetics; pharmacodynamics
• Description: Dual - acting antidepressants are relatively recent class of antidepressants. They are represented maintly by resotonin and norepinephrine reuptake inhibitors (SNRI), e. g. venlafaxine, milnacipran and duloxetine. The article deals with milnacipran. The new indication, fibromyalgia, is discussed in more details. Nowadays, the individualized treatment is emphasized. Certain differences in the pharamacodynamics and pharmacokinetics of SNRI may be important to tailor the treatment choice to the patient. Some case reports of patients successfully treated with milnacipran are described.

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