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Sarkom z interdigitujících dendritických buněk dolní končetiny rezistentní k vysokodávkované chemoterapii BEAM s autologní transplantací kmenových krvetvorných buněk - popis případu a přehled literatury
Title in English | Interdigitating dendritic cell sarcoma of low extremitis resistant to high dose chemotherapy BEAM with peripheral blood stem cell transplantation |
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Authors | |
Year of publication | 2009 |
Type | Article in Periodical |
Magazine / Source | Vnitřní lékařství |
MU Faculty or unit | |
Citation | |
Field | Oncology and hematology |
Keywords | stem cell; transplantation; sarcoma |
Description | Interdigitating dendritic cell sarcoma is a rare neoplasm forming part of the group of malignancies derived from histocytic cell line. This osological unit can be detected only by special immunohistochemical exams.To our knowledge, the above description is the first documented case of interdigitating dendritic cell sarcoma located in the tibia and crus soft tissue. We have not found any description of high-dose therapy supported by autologous transplantation of blood-forming tissue for this type of tumour in relevant literature. In this case, we record chemoresistance to high-dose chemotherapy and certain radiosensitivty of the tumour at the same time. |
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