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Publication details
Carvedilol and adrenergic agonists supress the lipopolysaccharide-induced NO production in RAW 264.7 macrophages via the adrenergic receptors
Authors | |
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Year of publication | 2009 |
Type | Article in Periodical |
Magazine / Source | Journal Physiology and Pharmacology |
MU Faculty or unit | |
Citation | |
Field | Physiology |
Keywords | carvedilol adrenergic agonists adrenergic antagonists macrophages nitric oxide |
Description | In this study, the effect of carvedilol on LPS-treated RAW 264.7 cells was investigated. It was demonstrated that carvedilol inhibits LPS-induced NO production and iNOS protein expression in macrophages and that these effects are mediated, at least in part, by the interaction of carvedilol with adrenergic receptors. |