Publication details

Monotherapy with low-dose thalidomide for relapsed or refractory multiple myeloma: better response rate with earlier treatment

Authors

MAISNAR Vladimír RADOCHA J. BÜCHLER Tomáš BLÁHA V. MALÝ J. HÁJEK Roman

Year of publication 2007
Type Article in Periodical
Magazine / Source European Journal of Haematology
MU Faculty or unit

Faculty of Medicine

Citation
Field Oncology and hematology
Keywords thalidomide; monotherapy; multiple myeloma; treatment; relapse
Description Thalidomide is an immunomodulatory drug used in the treatment of relapsed or refractory multiple myeloma (MM). The optimal dosing regimen of thalidomide is not known. Patients and Methods: We retrospectively analysed the overall response rate and response duration of 53 patients with relapsed MM who received thalidomide in a median dose of 100 mg daily. The aim of the study was to compare the response rates of thalidomide given as the second-line treatment to those of thalidomide given as the third-line therapy.

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