Publication details

Low-dose thalidomide regimens in therapy of relapsed or refractory multiple myeloma

Authors

ZEMANOVÁ M. ŠČUDLA Vlastimil ADAM Zdeněk GREGORA E. POUR Luděk MINAŘÍK J. PAVLÍČEK P. PIKA T. BAČOVSKÝ Jaroslav

Year of publication 2008
Type Article in Periodical
Magazine / Source Neoplasma
MU Faculty or unit

Faculty of Medicine

Citation
Field Oncology and hematology
Keywords multiple myeloma; resistance to therapy; thalidomide; cyclophosphamide; dexamethasone
Description Thalidomide has been estimated as a useful drug in therapy of refractory or relapsed multiple myeloma. Recently, several studies have shown very good results in therapy combination of thalidomide, cyclophosphamide and dexamethasone, but still high doses of thalidomide associated with serious adverse events have been used. In our study, we performed low-dose thalidomide regimens; the aim of this study was to verify the effect and to assess their toxicity.

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