Publication details
Bayesian Estimation of Mean Sojourn Time and Sensitivity in the Czech Organized Mammography Screening Programme
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| Year of publication | 2009 |
| Type | Appeared in Conference without Proceedings |
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| Citation | |
| Description | Organized breast cancer screening programme in the Czech Republic was initiated in September 2002. Free biennial preventive mammography examinations are offered to women aged 45-69. By year 2007 1,067,836 women were screened (more than 50% of the target population) in 1,611,582 examinations. A total of 7,835 cases of breast cancer were detected. Important parameters in assessing the quality of the programme and natural history of breast cancer are: mean duration of the preclinical screen-detectable phase (the carcinoma is without clinical signs but it could be found by the screening test - mammography), which is called mean sojourn time, and sensitivity of mammography (capability of the test to detect cancer). These parameters are not directly observable; however, they can be estimated using mathematical models. Both parameters were estimated for different age groups of women in target population. Simple tree-state Markov model with states: disease free - preclinical screen-detectable - clinical disease was developed and utilized for estimation. Analysis was performed using WinBUGS programme. |