Source-based morphometry of gray matter volume in the first-episode schizophrenia

• Authors: KAŠPÁREK Tomáš; MAREČEK Radek; SCHWARZ Daniel; PŘIKRYL Radovan; VANÍČEK Jiří; MIKL Michal; ČEŠKOVÁ Eva
• Year of publication: 2009
• Type: Article in Periodical
• Magazine / Source: European Archives of Psychiatry + Clinical Neuroscience
• MU Faculty or unit: Faculty of Medicine
• Keywords: schizophrenia, gray matter, morphometry
• Description: A novel approach to brain mophometry - source-based morphometry (SBM) - was used to assess regional gray matter volume in first-episode schizophrenia subjects. SBM, but not conventional voxel-based morphometry, was able to detect gray matter volume reduction in medial, lateral parts of prefrontal cortex, in superior temporal gyrus, and in cerebellum.

Related projects

• The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.