Možnosti modulace ATRA-indukované diferenciace neuroblastomových a meduloblastomových buněčných linií působením LOX/COX inhibitorů.

• Title in English: Possibilities to modulate ATRA-induced cell differentiation of neuroblastoma and medulloblastoma cell lines by LOX/COX inhibitors.
• Authors: RÉDOVÁ Martina; CHLAPEK Petr; LOJA Tomáš; ZITTERBART Karel; HERMANOVÁ Markéta; ŠTĚRBA Jaroslav; VESELSKÁ Renata
• Year of publication: 2009
• Type: Article in Proceedings
• Conference: XXXIII. Brněnské onkologické dny - edukační sborník
• MU Faculty or unit: Faculty of Science
• Field: Oncology and hematology
• Keywords: neuroblastoma; medulloblastoma; established cell lines; caffeic acid; celecoxibe; all-trans retinoic acid; cell differentiation
• Description: A detailed study of the effect of combined application of the LOX/COX inhibitors with ATRA in established neuroblastoma and medulloblastoma cell lines was performed using MTT-assay, immunoblotting, and flow cytometry.

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