Publication details
Protein engineering of carbohydrate binding proteins - understanding the recognition phenomena
| Authors | |
|---|---|
| Year of publication | 2009 |
| Type | Article in Proceedings |
| Conference | FEBS Journal |
| MU Faculty or unit | |
| Citation | |
| Field | Biophysics |
| Keywords | protein engineering;lectin; pathogen |
| Description | The contribution is focused on few examples where a combination of experimental methods (isothermal titration microcalorimetry, surface plasmon resonance, X-ray crystallography) with computational approaches can bring a significant profit for better understanding of protein-carbohydrate interactions on molecular level. Insight into structure correlation with function analysis of high-affinity lectins allows for construction of carbohydrate-binding proteins with tuned affinity and specificity for biotechnology and bioanalytical purposes. |
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