Vymizení nefrotického syndromu a zlepšení funkce ledvin u nemocné s light chain deposition disease po vysokodávkované chemoterapii s autologní transplantací kmenových krvetvorných buněk. Popis případu a přehled literatury

• Title in English: Complete remission of nephrotic syndrome and improvement of renal function in a patient with light chain deposition disease following high dose chemotherapy with transplantation of autologous haematopoietic stem cells. A case study and review of literatu
• Authors: ADAM Zdeněk; KREJČÍ Marta; POUR Luděk; ŠTĚPÁNKOVÁ Soňa; ČERMÁKOVÁ Z.; VOSKA L.; TEPLAN V.; KŘIVANOVÁ Andrea; HÁJEK Roman; MAYER Jiří
• Year of publication: 2009
• Type: Article in Periodical
• Magazine / Source: Vnitřní lékařství
• MU Faculty or unit: Faculty of Medicine
• Field: Oncology and hematology
• Keywords: Light chain deposition disease; multiple myeloma
• Description: We draw the reader's attention to the possibility of nephrotoxic effects of high dose melphalan (post conditioning renal insufficiency) in patients with nephrotic syndrome caused by light chain deposits as AL-amyloid or amorphous light chains deposits (LCDD)and we document the importance of plasma free light chain detection.

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