Publication details
Monitorování výskytu kontaktní senzibilizace na vybrané pomocné látky dermatologických extern a kosmetických přípravků u ekzematiků - výsledky a závěry vyplývající z řešení grantového projektu
| Title in English | Incidence monitoring of contact sensitization to selected adjuvants in dermatologic topical medications and cosmetics in patients with eczema - results and conclusions of a grant project |
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| Authors | |
| Year of publication | 2005 |
| Type | Article in Periodical |
| Magazine / Source | Česko-slovenská dermatologie |
| MU Faculty or unit | |
| Citation | |
| Field | Dermatovenerology |
| Keywords | contact sensitivity; adjuvants; preservatives; antioxidants |
| Description | In a group of nine hundred patients (mean age 43,6 years) with chronic eczema (males 289, females 611) examined in years 2001-2003 the frequency of sensitization to 28 selected adjuvants of topical dermatologic medications and cosmetics was evaluated by the method of skin patch tests. Four hundred, i.e. 44,4 % of patients was sensitized to at least one tested adjuvants. Clinical relevance was 32 %. In the group of patients with the primary diagnosis of atopic eczema (n 337) the frequency of sensitization to adjuvants was significantly lower compared with the group of non-atopic patients (n 563). The most frequent sources of sensitization were drugs 44,7 %, cosmetics 31,2 %, agents used in industry 7,8 % and health care 2,2 %, in 14,1 % the source was unknown. |
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