Publication details
Numerical defects in CD8+CD28- T-suppressor lymphocyte population in patients with type 1 diabetes mellitus and multiple sclerosis
Authors | |
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Year of publication | 2010 |
Type | Article in Periodical |
Magazine / Source | Cellular Immunology |
MU Faculty or unit | |
Citation | |
Field | Immunology |
Keywords | Type 1 diabetes mellitus; Multiple sclerosis; Autoimmune diseases; Regulatory T-cells; Suppressor cells |
Description | Type 1 diabetes mellitus and multiple sclerosis are organ-specific autoimmune diseases leading to an attack of auto-aggressive lymphocytes against the pancreatic beta-cells and central nervous system, respectively. Using four-colour flow cytometry, T-lymphocyte populations having an important function in autoimmune processes were analyzed. The observed data demonstrate significant differences among patients with T1D and MS in comparison to healthy individuals. |
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