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Způsob stanovení prognózy B-buněčné chronické lymfocytární leukémie
Title in English | Method for prognosis determination in B-cell chronic lymphocytic leukemia |
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Authors | |
Year of publication | 2010 |
Type | Patent |
MU Faculty or unit | |
Publisher | Úřad průmyslového vlastnictví |
State | Czech Republic |
Patent's number | 301540 |
Description | Method for prognosis determination of chronic lymphocytic leukemia in biological samples based on assesment of LAG3, ZAP70 and LPL gene expression. High expression of these genes correlates with unmutated immunoglobulin heavy chain variable segment gene, more agressive disease and shorter survival. |