Automated Electrochemical Analyzer as a New Tool for Detection of Thiols

• Authors: ADAM Vojtěch; FABRIK Ivo; KOHOUTKOVÁ Veronika; BABULA Petr; HUBÁLEK Jaromír; VRBA Radimír; TRNKOVÁ Libuše; KIZEK René
• Year of publication: 2010
• Type: Article in Periodical
• Magazine / Source: INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE
• MU Faculty or unit: Faculty of Science
• Field: Electrochemistry
• Keywords: Automated Electrochemical Detection; Drugs; Tumour Disease Markers; Proteins; Metallothioneins
• Description: Stationary electrochemical analysers are advantageous tools for detection of electroactive species. There advantages are low cost, sensitivity and repeatability. However, non-automated injection of samples belongs to their main disadvantages. We aim our attention to present a new electrochemical tool connected with unique autosampler enabling us to inject units of mu l, which is essential in for detection of biological samples. The analyser can be used for detection of peptides, proteins, nucleic acids, drugs. Moreover, the highest sensitivity has for thiols. The recent advances in the field of electrochemistry of mentioned biologically active compounds, mainly metallothionein, are also discussed.

Related projects

• Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)