Publication details

Zeptomole Electrochemical Detection of Metallothioneins

Authors

ADAM Vojtěch PETRLOVÁ Jitka WANG Joseph ECKSCHLAGER Tomáš TRNKOVÁ Libuše KIZEK René

Year of publication 2010
Type Article in Periodical
Magazine / Source PLoS ONE
MU Faculty or unit

Faculty of Science

Citation
Field Electrochemistry
Keywords PLASMA-MASS SPECTROMETRY; CANCER; CHRONOPOTENTIOMETRY; SPECIATION; PROTEOMICS; PROTEINS; LEVEL
Description Thiol-rich peptides and proteins possess a large number of biological activities and may serve as markers for numerous health problems including cancer. Metallothionein (MT), a small molecular mass protein rich in cysteine, may be considered as one of the promising tumour markers. The aim of this paper was to employ chronopotentiometric stripping analysis (CPSA) for highly sensitive detection of MT.

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