Publication details

On the Role of the cis Hoogsteen:Sugar-Edge Family of Base Pairs in Platforms and Triplets: Quantum Chemical Insights into RNA Structural Biology

Authors

SHARMA Purshotam SPONER Judit ŠPONER Jiří SHARMA Sitansh BHATTACHARYYA Dhananjay MITRA Abhijit

Year of publication 2010
Type Article in Periodical
Magazine / Source Jouranl of Physical Chemistry B
MU Faculty or unit

Faculty of Science

Citation
Field Physical chemistry and theoretical chemistry
Keywords quantum chemistry; base pairs; cis Hoogsteen/Sugar edge
Description Base pairs belonging to the cis Hoogsteen/sugar-edge (H:S) family play important structural roles in folded RNA molecules. We report results of analysis of 30 representative examples spanning 16 possible base pair combinations. The study, involving alternative classification of base pairs and triplets, provides insights into intrinsic properties of these base pairs and their possible structural and functional roles.
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