Metabolic ratio of dextromethorphan/dextrorphan in CYP2D6 phenotyping - identification of cut-off values in serum and corelation with urine levels

• Authors: JUŘICA Jan; ZENDULKA Ondřej; BARTEČEK Richard; ŽOURKOVÁ Alexandra; FLODROVÁ Eva; ZRŮSTOVÁ Jana; ŠULCOVÁ Alexandra
• Year of publication: 2010
• Type: Conference abstract
• MU Faculty or unit: Faculty of Medicine
• Description: The results of investigation of correlation of serum and urine dextromethorphan/dextrorphan metabolic ratio in CYP2D6 phenotyping were presented. Based on genetic analysis and values of MR, cutt off values (MRdem/dor) for separating extensive, poor and intermediate metabolizers were also identfied.

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