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Publication details
Successful treatment of life-threatening Candida peritonitis in a child with abdominal non-Hodgkin lymphoma using Efungumab and amphotericin B colloid dispersion.
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Year of publication | 2010 |
Type | Article in Periodical |
Magazine / Source | Journal of Pediatric Hematology and Oncology |
MU Faculty or unit | |
Citation | |
Field | Oncology and hematology |
Keywords | Candica peritonitis Efungumab amphotericin B colloid dispersion |
Description | Invasive fungal infections are serious complications of cancer therapy. We present a case report of a 12-year-old boy diagnosed with abdominal non-Hodgkin lymphoma and fecal and Candida peritonitis during induction chemotherapy. The invasive mycosis was managed using a combined approach of systemic antifungal agents including efungumab and surgical interventions. Efungumab, a recombinant antibody that inhibits extracellular heat shock protein 90, was used in combination with amphotericin B colloid dispersion after the failure of standard approaches. |