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Vztah progrese diabetické nefropatie a mortality k funkčnímu deficitu pentózového jako důsledku abnormálního metabolizmu thiaminu u DM
Title in English | Relation between progression of diabetic nephropathy and mortality and.the functional deficiency of pentose phosphate cycle enzymes as a result of abnormality in thiamine status in diabetic patients |
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Authors | |
Year of publication | 2010 |
Type | Article in Periodical |
Magazine / Source | Aktuality v nefrologii |
MU Faculty or unit | |
Citation | |
Field | Other medical specializations |
Keywords | diabetic nephropathy; pentose phosphate cycle; thiamin |
Description | The results support the role of functional thiamine deficiency in the development of hyperglycaemia- related pathology. Limited intracellular availability of active TKT co-factor seems to be a dominant abnormality. |
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