Abnormální metabolizmus thiaminu u DM jako důsledek funkčního deficitu pentózového cyklu a vztah k progresi diabetické nefropatie a mortalitě

• Title in English: Abnormal thiamin metabolism caused by functional deficit of pentose phoshate cycle and relation to progression of diabetic nephropathy and mortality
• Authors: KRUSOVÁ Darja; PÁCAL Lukáš; KAŇKOVÁ Kateřina; SVOJANOVSKÝ Jan; TOMANDL Josef; OLŠOVSKÝ Jindřich
• Year of publication: 2010
• Type: Conference abstract
• MU Faculty or unit: Faculty of Medicine
• Description: The results support the role of functional thiamine deficiency in the development of hyperglycaemia- related pathology. Limited intracellular availability of active TKT co-factor seems to be a dominant abnormality.

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