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Publication details
Mutagenesis of Lectin PA-IIL from Pseudomonas aeruginosa as a Tool for Preparation of Lectins with Tune Specificity and Affinity
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Year of publication | 2010 |
Type | Conference abstract |
MU Faculty or unit | |
Citation | |
Description | Carbohydrate-mediated recognition plays an important role in the ability of pathogenic bacteria to adhere to the surface of the host cell in the first step of their invasion and infectivity. A saturated mutagenesis of the specificity binding loop of PA-IIL lectin in silico was performed and selected mutants have been studied in vitro. |
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