Ztráta kopie genu pro EGFR u pacienta s multiformním glioblastomem: případová studie a analýza derivované linie.

• Title in English: A loss of EGFR gene copy in glioblastoma multiforme: a case report and analysis of derived cell line.
• Authors: NERADIL Jakub; ŠKODA Jan; LOJA Tomáš; ZITTERBART Karel; PAVELKA Zdeněk; ŠMARDOVÁ Jana; VALÁŠKOVÁ Iveta; HERMANOVÁ Markéta; ŠTĚRBA Jaroslav; VESELSKÁ Renata
• Year of publication: 2010
• Type: Conference abstract
• MU Faculty or unit: Faculty of Science
• Description: This study is focused on the analysis of glioblastoma multiforme in patient experienced very long event-free survival after surgery and adjuvant radiotherapy and chemotherapy. Tumor tissue as well as derived HGG-02 cell line were analyzed using molecular biology and molecular cytogenetic methods. The most important finding is a loss of EGFR gene copy in both the tumor tissue and the HGG-02 cell line.

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