Publication details

Eotaxin gen -426C-T, -384A-G and 67G-A single-nucleotide polymorphisms and atopic dermatitis in Czech adult AD patients

Authors

KOZÁČIKOVÁ Zuzana PETRUCHA V. TRHANOVÁ K. VAŠKŮ Anna

Year of publication 2010
Type Article in Proceedings
Conference 7th Spring Symposium, EADV Cavtat 2010, Chorvatsko, 13.-16.5.2010 - Abstrakta na CD
MU Faculty or unit

Faculty of Medicine

Citation
Web http://www.eadvcavtat2010.com
Field Dermatovenerology
Keywords genetic of atopic dermatitis; eotaxin gen
Description Eotaxin may play an important role in atopic dermatitis as a potent immunomodulatory agent. In a pilot study, three single-nucleotide polymorphisms (-426C-T, -384A-G and 67G-A ) of the eotaxin gene were associated with some phenotypes of the AD patients. Detection of this polymorphisms seems to be a promising way for finding of clinically valid gene biomarkers for the disease.

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