Publication details
Quality of Newly Formed Cartilaginous Tissue in Defects of Articular Surface after Transplantation of Mesenchymal Stem Cells in a Composite Scaffold Based on Collagen I with Chitosan Micro- and Nanofibres
| Authors | |
|---|---|
| Year of publication | 2010 |
| Type | Article in Periodical |
| Magazine / Source | Physiol. Res. |
| MU Faculty or unit | |
| Citation | |
| Field | Traumatology and orthopaedic surgery |
| Keywords | bone marrow mesenchymal stem cells;allogeneic;micropicking;articular cartilage |
| Description | It follows from the above-said that treatment of iatrogenic lesions of the surface of articular cartilage on femur condyles in miniature pigs after transplantation of mesenchymal stem cells in a composite scaffold based on collagen I containing micro- and nanofibers from chitosan resulted in filling of tissue defects in a hyaline type of cartilage. Lesions treated by implantation of scaffold alone or by micropicking were filled with fibrous cartilage with inferior macroscopic, histological and immunohistochemical parameters. |
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