Publication details
Haplotypes of the IL-1 Gene Cluster are Associated With Gastroesophageal Reflux Disease and Barrett’s Esophagusin the Czech Population
| Authors | |
|---|---|
| Year of publication | 2011 |
| Type | Conference abstract |
| MU Faculty or unit | |
| Citation | |
| Description | Gastroesophageal reflux (GERD) is a major public health problem in the Western world that can lead to a number of complications, such as reflux esophagitis (RE), Barrett’s esophagus (BE), and adenocarcinoma. It has been postulated that a strong pro-inflammatory host response predisposes to disease. Although no significant role of single IL-1 variants in reflux disease was found, our results indicate that IL-1 haplotypes may be associated with susceptibility to GERD and Barrett’s esophagus. |
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