Publication details
Regrese osteolytického ložiska u pacienta s mnohočetným myelomem léčeného klodronátem po úspěšné terapii režimem s bortezomibem
| Title in English | Regression of an Osteolytic Lesion in Patient with Multiple Myeloma Treated with Clodronate after a Successful Therapy with Bortezomib-based Regimen |
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| Authors | |
| Year of publication | 2011 |
| Type | Article in Periodical |
| Magazine / Source | Klinická onkologie |
| MU Faculty or unit | |
| Citation | |
| Field | Oncology and hematology |
| Keywords | ;multiple myeloma; bortezomib; bisphosphonates; osteolysis; osteogenesis; radiography |
| Description | Osteolytic lesions are a common manifestation of multiple myeloma, though their healing is rare in these patients. Generally, during a complete remission, lesions only stop progressing; radiologically evident recalcification is exceptional. Herein we report a case of a male patient born in 1941 and diagnosed in 2005 with IgA multiple myeloma presenting with multiple osteolytic bone lesion. A complete remission of the disease after an administration of bortezomib (Velcade) based regimen in long-term clodronate (Bonefos) treated patient with relapsed multiple myeloma is radiographically apparent by clear healing signs of the osteolytic bone lesion. |
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