Publication details
Levels of nestin protein correlate with 1q21 gain and hyperdiploidy in multiple myeloma
| Authors | |
|---|---|
| Year of publication | 2011 |
| Type | Conference abstract |
| MU Faculty or unit | |
| Citation | |
| Description | Nestin is considered to be a suitable diagnostic and prognostic indicator of malignancy and a marker of cancer stem cells in solid tumors. The aim of this study was to correlate nestin levels with cytogenetic abnormalities in PC of MM patients. Our results indicate that high % Nes+PC or nestin levels significantly correlate with 1q21 gain, and low nestin levels correlate with HY. We suppose that nestin could associate with unfavorable prognosis but further studies are required to elucidate its clinical implication for MM |
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