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Publication details
Enhancement of psychostimulant effect and development of behavioural sensitisation to methamphetamine in mice by combined treatment with piracetam
Authors | |
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Year of publication | 2011 |
Type | Article in Periodical |
Magazine / Source | Activitas Nervosa Superior Rediviva |
MU Faculty or unit | |
Citation | |
Field | Pharmacology and pharmaceutical chemistry |
Keywords | methamphetamine; piracetam; behavioural sensitisation; mice; open field test |
Description | Piracetam in our experiment enhanced acute effects of methamphetamine as well as development of sensitisation to its stimulatory effects. Background of these pharmacological drug-drug interactions remains unclear. Although clinically piracetam itself shows minimal adverse effects and toxicity, its combination with methamphetamine could worsen the negative drug abuse consequences. |
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