Publication details
Etorikoxib v premedikaci před tonzilektomií
| Title in English | Premedication with etoricoxib before tonsillectomy |
|---|---|
| Authors | |
| Year of publication | 2011 |
| Type | Article in Periodical |
| Magazine / Source | Anesteziologie a intenzivní medicína |
| MU Faculty or unit | |
| Citation | |
| Web | http://www.prolekare.cz/anesteziologie-intenzivni-medicina-clanek?id=35740 |
| Field | Other medical specializations |
| Keywords | premedication with etoricoxib; tonsillectomy; cyclooxygenase-2 inhibitors |
| Description | The goal of the study was to determine the analgesic effect of etoricoxib administered before tonsillectomy. The study included adult ASA I and II patients undergoing simple tonsillectomy. The surgical procedure was performed under general anaesthesia with orotracheal intubation. Total 75 patients were randomised into two groups, etoricoxib (n = 38) and control (n = 37). The primary outcome was post-tonsillectomy pain using VAS. We analysed the postoperative analgesic consumption (metamizol vs. piritramid) during the first 24 hours after tonsillectomy. We also evaluated the quality of postoperative pain control and the relative incidence in the two groups. The secondary outcomes included the incidence of post-tonsillectomy bleeding and the need for surgical reoperation for haemostasis. The results showed a statistically significant reduction in the analgesic consumption after 3 and 24 hours in the etoricoxib group. There were significant differences between the groups in the quality of pain control in the etoricoxib vs. control group as well as the type of the pain. Analysis of VAS showed a stable intensity of pain during the first 24 hours in the etoricoxib group. We observed a lower overall consumption of non-opioid postoperative analgesia, better quality of pain control and relatively stable intensity of pain in the etoricoxib group. |