Plant aminoaldehyde dehydrogenases oxidize a wide range of nitrogenous heterocyclic aldehydes

• Authors: FROMMEL Jan; SOURAL Miroslav; TYLICHOVÁ Martina; KOPEČNÝ David; DEMO Gabriel; WIMMEROVÁ Michaela; ŠEBELA Marek
• Year of publication: 2012
• Type: Article in Periodical
• Magazine / Source: Amino Acids
• MU Faculty or unit: Central European Institute of Technology
• web: http://link.springer.com/article/10.1007%2Fs00726-011-1174-x#page-1
• Doi: http://dx.doi.org/10.1007/s00726-011-1174-x
• Field: Biochemistry
• Keywords: aldehyde; aminoaldehyde dehydrogenase; pyridine; pyrimidine; purine

Attached files

• 2012_AA.pdf

• Description: The metabolic degradation of aldehydes is catalyzed by oxidoreductases from which aldehyde dehydrogenases comprise a nonspecific or substrate specific enzymes. Recombinant isoenzymes from pea and tomato were subjected to kinetic measurments with synthetic aldehydes containing a nitrogenous heterocycle such as pyridinecarbaldehydes and their halogenated derivatives.

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