Publication details

Systematic Comparisons of Electrocardiographic Morphology Increase the Precision of QT Interval Measurement

Authors

HNATKOVA Katerina SMETANA Peter TOMAN Ondřej BAUER Axel SCHMIDT G. MALIK Marek

Year of publication 2009
Type Article in Periodical
Magazine / Source PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
MU Faculty or unit

Faculty of Medicine

Citation
Doi http://dx.doi.org/10.1111/j.1540-8159.2009.02185.x
Field Other medical specializations
Keywords thorough QT
Description Decreased intrasubject variability of QTc values is needed to increase the power and reduce the size of the so-called thorough QT studies. One source of QTc variability is the lack of systematic measurements when electrocardiograms (ECG) with closely matching morphologies are not measured in an exactly corresponding way. The inaccuracy can be eliminated by postprocessing of QT measurements by ECG pattern matching. This study tested the effects of pattern matching in ECG measurements in two populations of healthy subjects (n = 48 56) and in a population of patients with advanced Parkinson

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