Publication details

MiR-34b is associated with clinical outcome in triple-negative breast cancer patients.

Authors

SVOBODA Marek ŠÁNA Jiří RÉDOVÁ Martina NAVRÁTIL Jiří PALÁCOVÁ Markéta FABIAN Pavel SLABÝ Ondřej VYZULA Rostislav

Year of publication 2012
Type Article in Periodical
Magazine / Source Diagnostic Pathology
MU Faculty or unit

Faculty of Medicine

Citation
Web http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349474/?tool=pubmed
Doi http://dx.doi.org/10.1186/1746-1596-7-31
Field Oncology and hematology
Keywords triple-negative breast cancer; miR-34a; miR-34b; miR-34c; prognosis
Description Breast cancer is the most common malignancy with the highest incidence rates among women worldwide. Triple-negative breast cancer (TNBC) represents the major phenotype of basal-like molecular subtype of breast cancer, characterized by higher incidence in young women and a very poor prognosis. MicroRNAs (miRNAs) are small non-coding RNAs playing significant role in the pathogenesis of many cancers including breast cancer. Therefore, miRNAs are also potential prognostic and/or predictive biomarkers in triple-negative breast cancer patients.

You are running an old browser version. We recommend updating your browser to its latest version.

More info