Publication details
Circulating miR-378 and miR-451 in serum are potential biomarkers for renal cell carcinoma
| Authors | |
|---|---|
| Year of publication | 2012 |
| Type | Article in Periodical |
| Magazine / Source | Journal of Translational Medicine |
| MU Faculty or unit | |
| Citation | |
| Web | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340316/?tool=pubmed |
| Doi | http://dx.doi.org/10.1186/1479-5876-10-55 |
| Field | Oncology and hematology |
| Keywords | Renal cell carcinoma; MicroRNA; Serum; Biomarker |
| Description | There is no standard serum biomarker used for diagnosis or early detection of recurrence for renal cell carcinoma (RCC) patients. MicroRNAs (miRNAs) are abundant and highly stable in blood serum, and have been recently described as powerful circulating biomarkers in a wide range of solid cancers. Our aim was to identify miRNA signature that can distinguish the blood serum of RCC patients and matched healthy controls and validate identified miRNAs as potential biomarkers for RCC. |
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