Publication details

MCP-1 AND RANTES CHEMOKINES AND FACTORS DESCRIBING RHEUMATOID ARTHRITIS

Authors

PÁVEK Nikolas LIPKOVÁ Jolana NĚMEC Petr GATTEROVA Jindra SOUČEK Miroslav VAŠKŮ Anna GOLDBERGOVÁ Monika

Year of publication 2012
Type Conference abstract
Citation
Description The MCP-1/CCL2 as well as RANTES/CCL5 chemokines are potent chemoattractant involved in immunoregulatory and inflammatory processes incisive rheumatoid arthritis. Inour study we found a significant increase in the prevalence of the heterozygous variant of the -855C/G MCP-1 polymorphism compared to homozygous variants in the IgM RF-positive subgroup of RA patients. Furthermore, an association of RANTES -403 G/A promoter polymorphism to circulating levels of IL15 and IL10 was found.
Related projects:

You are running an old browser version. We recommend updating your browser to its latest version.

More info