Publication details
Clinical Outcomes of Patients with Nonseminomatous Germ Cell Tumours and Negative Postchemotherapy Positron Emission Tomography
| Authors | |
|---|---|
| Year of publication | 2012 |
| Type | Article in Periodical |
| Magazine / Source | Cancer Investigation |
| MU Faculty or unit | |
| Citation | |
| Doi | http://dx.doi.org/10.3109/07357907.2012.679347 |
| Field | Oncology and hematology |
| Keywords | Positron emission tomography; Germ cell tumour; Testicular cancer; Diagnosis; Relapse |
| Attached files | |
| Description | Univariate and multivariate analyses were carried out to identify factors associated with the failure of 18-fluorodeoxyglucose positron emission tomography (FDG-PET) to correctly predict relapse-free survival in patients with nonseminomatous germ cell tumours. Ninety-three patients with negative postchemotherapy FDG-PET scan were analyzed in the retrospective study. The FDG-PET result was validated by long-term follow-up and, in some patients, by resection of the residual tumour mass. The negative predictive value of FDG-PET was 81.7%. Higher tumour marker levels and nodal stage at diagnosis, presence of residual mass, and teratoma or teratocarcinoma in the primary histology were associated with FDG-PET failure. |