Publication details

Developmental silencing of the AtTERT gene is associated with increased H3K27me3 loading and maintenance of its euchromatic environment

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Authors

OGROCKÁ Anna SÝKOROVÁ Eva FAJKUS Jiří FOJTOVÁ Miloslava

Year of publication 2012
Type Article in Periodical
Magazine / Source Journal of Experimental Botany
MU Faculty or unit

Central European Institute of Technology

Citation
Web http://jxb.oxfordjournals.org/content/63/11/4233
Doi http://dx.doi.org/10.1093/jxb/ers107
Field Genetics and molecular biology
Keywords Arabidopsis thaliana; developmental regulation; DNA methylation; histone modifications; telomerase
Description elomerase is precisely regulated during development and in animals, involvement of the epigenetic mechanisms to the regulation of the telomerase reverse transcriptase (TERT) gene transcription was reported. In Arabidopsis thaliana model plant, low level of methylated cytosines in the TERT upstream region was detected in both telomerase-positive and telomerase-negative tissues and AtTERT chromatin maintained the euchromatic nature despite the increased H3K27me3 loading in telomerase-negative tissue. These results may reflect a unique attribute of plants – their totipotency - which accords with a reversible and dynamic character of telomerase silencing.
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