Mgr. Miroslav Vařecha, Ph.D.
Počet publikací: 55
2021
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Loss of Sprouty produces a ciliopathic skeletal phenotype in mice through elongation of primary cilia and upregulation of Hedgehog signaling
Rok: 2021, druh: Konferenční abstrakty
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Loss of Sprouty Produces a Ciliopathic Skeletal Phenotype in Mice Through Upregulation of Hedgehog Signaling
Journal of Bone and Mineral Research, rok: 2021, ročník: 36, vydání: 11, DOI
2020
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Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling
EMBO MOLECULAR MEDICINE, rok: 2020, ročník: 12, vydání: 11, DOI
2019
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Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase
Proceedings of the National Academy of Sciences of the United States of America, rok: 2019, ročník: 116, vydání: 10, DOI
2018
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Nanodiamonds as "artificial proteins": Regulation of a cell signalling system using low nanomolar solutions of inorganic nanocrystals
Biomaterials, rok: 2018, ročník: 176, vydání: SEP 2018, DOI
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Proteomic analyses of signalling complexes associated with receptor tyrosine kinase identify novel members of fibroblast growth factor receptor 3 interactome
Cellular Signalling, rok: 2018, ročník: 42, vydání: JAN 2018, DOI
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Regulation of ciliary function by fibroblast growth factor signaling identifies FGFR3-related disorders achondroplasia and thanatophoric dysplasia as ciliopathies
Human molecular genetics, rok: 2018, ročník: 27, vydání: 6, DOI
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The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases
SCIENCE SIGNALING, rok: 2018, ročník: 11, vydání: 548, DOI
2017
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ARQ 087 inhibits FGFR signaling and rescues aberrant cell proliferation and differentiation in experimental models of craniosynostoses and chondrodysplasias caused by activating mutations in FGFR1, FGFR2 and FGFR3
Bone, rok: 2017, ročník: 105, vydání: DEC 2017, DOI
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Differences in anterior-posterior sensitivity of early limb bud cell to FGF/WNT treatment
Rok: 2017, druh: Konferenční abstrakty