Informace o projektu
Involvement of Czech Translational Medicine Infrastructure to the European Advanced Translational Research Infrastructure in Medicine
(EATRIS-ERIC-CZ)
- Kód projektu
- LM2015064
- Období řešení
- 1/2016 - 12/2019
- Investor / Programový rámec / typ projektu
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Ministerstvo školství, mládeže a tělovýchovy ČR
- Velké infrastruktury pro výzkum, vývoj a inovace
- Fakulta / Pracoviště MU
- Středoevropský technologický institut
- Spolupracující organizace
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Mikrobiologický ústav AV ČR, v. v. i.
Ústav experimentální medicíny AV ČR, v. v. i.
Ústav jaderné fyziky AV ČR, v. v. i.
Ústav makromolekulární chemie AV ČR, v. v. i.
Ústav organické chemie a biochemie AV ČR, v. v. i.
Univerzita Karlova
Univerzita Palackého v Olomouci
- Odpovědná osoba MUDr. Marián Hajdúch, Ph.D.
In 2011, the Czech Republic acceded to the European Advanced Translational Research Infrastructure in Medicine (EATRIS) consortium and this transitional phase lasted even in 2013. EATRIS entered in fall 2013 to ERIC (EATRIS-ERIC) and the Czech Republic became one of the founding countries. At the national level, the national node was built according to the schedule in 2010-2014 (Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc - IMTM), and in 2013/2014 we have created the national network, where the following institutions joined: Institute of Chemical Technology Prague (ICT), Institute of Organic Chemistry and Biochemistry AS CR, v.v.i. (IOCB), Charles University in Prague, First Faculty of Medicine (CU), Institute of Macromolecular Chemistry AS CR, v.v.i. (IMC), Masaryk University, Central-European Technology Institute (CEITEC), Nuclear Physics Institute of the ASCR, v.v.i. (NPI), Institute of Microbiology AS CR, v.v.i. (IM). Majority of these institutions have already signed an access agreement to EATRIS-ERIC
(http://www.eatris.eu/about/simpleinstitutions.html). Czech institutions are actively involved in the
activities of platforms Small Molecules, Biomarkers, Vaccines, and Imaging and Tracing. The mission of the current infrastructure project proposal EATRIS-ERIC-CZ is to further develop a dynamic and collaborative environment that will support chemical, biomedical, and clinical research, and speed up its transfer into clinical practice. It will connect and facilitate collaboration of top national research institutions and hospitals in the research partnership. EATRIS-ERIC-CZ will lead to the development of new knowledge and it will place the Czech Republic among nationally and internationally recognized centres of excellence in molecular and translational medicine directly linked to EATRIS-ERIC and other major biomedical infrastructures.
Publikace
Počet publikací: 14
2024
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Critical appraisal of the piRNA-PIWI axis in cancer and cancer stem cells
BIOMARKER RESEARCH, rok: 2024, ročník: 12, vydání: 1, DOI
2021
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A verified genomic reference sample for assessing performance of cancer panels detecting small variants of low allele frequency
GENOME BIOLOGY, rok: 2021, ročník: 22, vydání: 1, DOI
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Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions
GENOME BIOLOGY, rok: 2021, ročník: 22, vydání: 1, DOI
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Genomic arrays identify high-risk chronic lymphocytic leukemia with genomic complexity: a multicenter study
Haematologica, rok: 2021, ročník: 106, vydání: 1, DOI
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In-Cell NMR Spectroscopy of Functional Riboswitch Aptamers in Eukaryotic Cells
Angewandte Chemie International Edition, rok: 2021, ročník: 60, vydání: 2, DOI
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Whole exome sequencing reveals NOTCH1 mutations in anaplastic large cell lymphoma and points to Notch both as a key pathway and a potential therapeutic target
haematologica, rok: 2021, ročník: 106, vydání: 6, DOI
2019
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Monitoring DNA-Ligand Interactions in Living Human Cells Using NMR Spectroscopy
Journal of the American Chemical Society, rok: 2019, ročník: 141, vydání: 34, DOI
2018
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Evaluation of the Stability of DNA i-Motifs in the Nuclei of Living Mammalian Cells
Angewandte Chemie International Edition, rok: 2018, ročník: 57, vydání: 8, DOI
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Identification of microRNAs differentially expressed in glioblastoma stem-like cells and their association with patient survival
Scientific reports, rok: 2018, ročník: 8, vydání: FEB, DOI
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Low-burden TP53 mutations in chronic phase of myeloproliferative neoplasms: association with age, hydroxyurea administration, disease type and JAK2 mutational status
Leukemia, rok: 2018, ročník: 32, vydání: 2, DOI