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Informace o projektu
Czech Infrastructure for Integrative Structural Biology
(CIISB)
- Kód projektu
- LM2015043
- Období řešení
- 1/2016 - 12/2019
- Investor / Programový rámec / typ projektu
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Ministerstvo školství, mládeže a tělovýchovy ČR
- Velké infrastruktury pro výzkum, vývoj a inovace
- Fakulta / Pracoviště MU
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Středoevropský technologický institut
- prof. RNDr. Vladimír Sklenář, DrSc.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed infrastructure of the core facilities and central laboratories of CEITEC (Central European Institute of Technology, Brno) and BIOCEV (Biotechnology and Biomedicine Centre, Vestec, Prague-West) providing expertise and access to technologies used for integrative approaches to structural analysis of biologically important cellular components and macromolecules - proteins, nucleic acids, and their complexes. CIISB, equipped with the cutting-edge technologies (total investments will exceed 750 mil. CZK by the end of 2015), will offer access to the equipment and expertise in the following fields: high-field NMR spectroscopy; high throughput crystallization of biological macromolecules; X-ray diffraction techniques; Bio-SAXS measurements; AFM imaging; characterization of proteins, nucleic acids and complexes by biophysical methods including microcalorimetry, dynamic light scattering, and surface plasmon resonance; high-end cryo-electron microscopy and tomography allowing studies of cellular structures, organelles, and biomacromolecular complexes by 3D imaging; protein expression in eukaryotic cells; high-end mass spectrometry characterization of biomacromolecules; determination of protein post-translational modifications; MS-based peptide mapping/sequencing; high throughput sequencing and proteomic services. CIISB infrastructure aims to provide a high quality open access services in provision of methods and techniques on a level of national and trans-national importance. CIISB as National Affiliated Center is a part of the ESFRI projects INSTRUCT.
Publikace
Počet publikací: 312
2018
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Advanced and Rationalized Atomic Force Microscopy Analysis Unveils Specific Properties of Controlled Cell Mechanics
Frontiers in Physiology, rok: 2018, ročník: 9, vydání: AUG 17 2018, DOI
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Alumazene Reactivity with Quinolinols - Addition and Substitution Reactions on the Al3N3 Ring
Acta Chimica Slovenica, rok: 2018, ročník: 65, vydání: 4, DOI
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Automated NMR resonance assignments and structure determination using a minimal set of 4D spectra
Nature Communications, rok: 2018, ročník: 9, vydání: JAN, DOI
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Bambusurils Bearing Nitro Groups and Their Further Modifications
European Journal of Organic Chemistry, rok: 2018, ročník: Neuveden, vydání: 1, DOI
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Bio-Inspired Hydro-Pressure Consolidation of Silica
Advanced Functional Materials, rok: 2018, ročník: 28, vydání: 48, DOI
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BioSAXS practical course
Rok: 2018, druh: Uspořádání workshopu
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BUT students from Faculty of chemistry
Rok: 2018, druh: Popularizační texty
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Comparative investigation of toxicity and bioaccumulation of Cd-based quantum dots and Cd salt in freshwater plant Lemna minor L.
Ecotoxicology and Environmental Safety, rok: 2018, ročník: 147, vydání: JAN 2018, DOI
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Complete genome sequences of two strains of Treponema pallidum subsp pertenue from Indonesia: Modular structure of several treponemal genes
PLoS neglected tropical diseases, rok: 2018, ročník: 12, vydání: 10, DOI
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Controlled synthesis and characterization of metal alloy nanoparticles and their size-dependent phase diagrams
Rok: 2018, druh: Konferenční abstrakty