Informace o projektu
European Human Biomonitoring Initiative
(HBM4EU)
- Kód projektu
- 733032
- Období řešení
- 1/2017 - 6/2022
- Investor / Programový rámec / typ projektu
-
Evropská unie
- Horizon 2020
- Health, demographic change and wellbeing (Societal Challenges)
- Fakulta / Pracoviště MU
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Přírodovědecká fakulta
- prof. RNDr. Jana Klánová, Ph.D.
- Mgr. Ondřej Adamovský, Ph.D.
- Lola Murielle Bajard ép.Esner, Ph.D.
- prof. RNDr. Luděk Bláha, Ph.D.
- doc. RNDr. Pavel Čupr, Ph.D.
- Elena Dominguez Romero, PhD.
- Mgr. Klára Komprdová, Ph.D.
- Ing. Štěpán Koudelka, Ph.D.
- RNDr. Ondřej Májek, Ph.D.
- Lisa Emily Melymuk, Ph.D.
- Chander Kant Negi, Ph.D.
- Mgr. Ondřej Ngo, Ph.D.
- Ing. Šárka Palátová, Ph.D.
- Veronika Janina Schacht, Ph.D.
- Mgr. Libor Šulc, Ph.D.
- Jakub Vinkler, DiS.
- Chiara Maria Vitale, PhD
- Spolupracující organizace
-
Ústav experimentální medicíny AV ČR, v. v. i.
- Odpovědná osoba MUDr. Radim Šrám, DrSc.
- Odpovědná osoba prof. MUDr. Milena Králíčková, Ph.D.
- Odpovědná osoba prof. Ing. Jana Hajšlová, CSc.
- Odpovědná osoba Ing. Adéla Fraňková, Ph.D.
- Odpovědná osoba Gorazd B. Stokin
- Odpovědná osoba RNDr. Ondřej Májek, Ph.D.
- Odpovědná osoba Marike Kolossa-Gehring
The overarching goal of the European Human Biomonitoring Initiative is to generate knowledge to inform the safe management of chemicals and so protect human health. We will use human biomonitoring to understand human exposure to chemicals and resulting health impacts and will communicate with policy makers to ensure that our results are exploited in the design of new chemicals policies and the evaluation of existing measures.
Key objectives include:
- Harmonizing procedures for human biomonitoring across 26 countries, to provide policy makers with comparable data on human internal exposure to chemicals and mixtures of chemicals at EU level;
- Linking data on internal exposure to chemicals to aggregate external exposure and identifying exposure pathways and upstream sources. Information on exposure pathways is critical to the design of targeted policy measures to reduce exposure;
- Generating scientific evidence on the causal links between human exposure to chemicals and negative health outcomes; and
- Adapting chemical risk assessment methodologies to use human biomonitoring data and account for the contribution of multiple external exposure pathways to the total chemical body burden.
We will achieve these objectives by harmonizing human biomonitoring initiatives in 26 countries, drawing on existing expertise and building new capacities. By establishing National Hubs in each country to coordinate activities, we will create a robust Human Biomonitoring Platform at European level. This initiative contributes directly to the improvement of health and well-being for all age groups, by investigating how exposure to chemicals affects the health of different groups, such as children, pregnant women, foetuses and workers. We will also investigate how factor such as behavior, lifestyle and socio-economic status influence internal exposure to chemicals across the EU population. This knowledge will support policy action to reduce chemical exposure and protect
health.
Publikace
Počet publikací: 51
2022
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Personal care product use and lifestyle affect phthalate and DINCH metabolite levels in teenagers and young adults
Environmental Research, rok: 2022, ročník: 213, vydání: October 2022, DOI
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Pesticide exposure among Czech adults and children from the CELSPAC-SPECIMEn cohort: Urinary biomarker levels and associated health risks
Environmental Research, rok: 2022, ročník: 214, vydání: November 2022, DOI
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Providing Biological Plausibility for Exposure-Health Relationships for the Mycotoxins Deoxynivalenol (DON) and Fumonisin B1 (FB1) in Humans Using the AOP Framework
Toxins, rok: 2022, ročník: 14, vydání: 4, DOI
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Pyrethroids and developmental neurotoxicity-A critical review of epidemiological studies and supporting mechanistic evidence
Environmental Research, rok: 2022, ročník: 214, vydání: November 2022, DOI
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Risk Factors Associated with the Consumption of Sugar-Sweetened Beverages among Czech Adults: The Kardiovize Study
Nutrients, rok: 2022, ročník: 14, vydání: 24, DOI
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Suspect and non-targeted screening-based human biomonitoring identified 74 biomarkers of exposure in urine of Slovenian children
Environmental Pollution, rok: 2022, ročník: 313, vydání: November 2022, DOI
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The Association between ADHD and Environmental Chemicals-A Scoping Review
International Journal of Environmental Research and Public Health, rok: 2022, ročník: 19, vydání: 5, DOI
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The NORMAN Suspect List Exchange (NORMAN-SLE): facilitating European and worldwide collaboration on suspect screening in high resolution mass spectrometry
Environmental Sciences Europe, rok: 2022, ročník: 34, vydání: 1, DOI
2021
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An adverse outcome pathway based in vitro characterization of novel flame retardants-induced hepatic steatosis
Environmental Pollution, rok: 2021, ročník: 289, vydání: November 2021, DOI
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Endocrine disrupting potential of replacement flame retardants-Review of current knowledge for nuclear receptors associated with reproductive outcomes
Environment International, rok: 2021, ročník: 153, vydání: August 2021, DOI