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miR-17-5p Regulates Endocytic Trafficking through Targeting TBC1D2/Armus
Autoři | |
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Rok publikování | 2012 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | PLoS One |
Fakulta / Pracoviště MU | |
Citace | |
Doi | http://dx.doi.org/10.1371/journal.pone.0052555 |
Obor | Využití počítačů, robotika a její aplikace |
Klíčová slova | Cancer cell-proliferation; epidermal-grow-factor; endosomal traficking; application of image analysis |
Popis | We have developed an image analysis approach for segmentation and classification of cell nuclei that was used in a study of the regulation of endocytic trafficking. A novel function of miR-17 was discovered, which might act cooperatively with other functions of miR-17 and related miRNAs in health and disease. |
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