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Voltage Sensitive Dye di-4-ANNEPS Prolongs Impulse Conduction Through Ventricles, but not Through AV Node in Isolated Rabbit Heart
Název česky | Napěťově citlivá barva di-4-ANNEPS na izolovaném kraličím srdci prodložuje vedení komorami, ale ne AV uzlem |
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Autoři | |
Rok publikování | 2015 |
Druh | Článek ve sborníku |
Konference | Computing in Cardiology, 2015. |
Fakulta / Pracoviště MU | |
Citace | |
Obor | Fyziologie |
Klíčová slova | heart; di-4-ANNEPS; electrogram |
Popis | Voltage sensitive dye di-4-ANEPPS is widely used in studies of cardiac electrophysiology. Although reduction of cardiac impulse propagation and prolongation of RR interval in the presence of di-4-ANEPPS is known, the effect on impulse conduction through AV node has not been studied yet. In this study the quantification of di-4-ANEPPS impact on duration of impulse conduction through AV node and ventricles in isolated rabbit hearts was done. It can be concluded that voltage sensitive dye di-4-ANEPPS leads to prolongation of cardiac impulse conduction through the ventricles. Conduction through AV node is impaired only slightly. |
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